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Angioedema

So what exactly is angioedema? It is swelling beneath the skin in the deeper layers of the skin and it usually occurs around the mouth (especially the lips) and the throat. The throat swelling, if not treated quickly, will gradually close off the airway which will eventually lead to difficulty breathing and swallowing.

The good thing (if I can say that) about angioedema is that it usually happens pretty soon after taking a medication... the bad thing about it is that you have to treat it about as quickly as it happens! Have I scared you enough? Okay then, I'll stop... here's a list of drugs that commonly cause this particular side effect. Please do note however that many, many drugs can cause angioedema, in fact, almost every drug has the propensity to cause it.

Drug Classes That Most
Commonly Cause Angioedema

  • ACE Inhibitors
  • Angiotensin Receptor Blockers (ARBs)
  • Antibiotics
  • COX-2 Inhibitors
  • NSAIDs
  • Proton Pump Inhibitors
  • Selective Serotonin Reuptake Inhibitors (SSRIs)
  • Statins
  • Sulfa Drugs
  • Vaccines


ACE Inhibitors

  • Benazepril (Lotensin)
  • Captopril (Capoten)
  • Enalapril (Vasotec)
  • Fosinopril (Monopril)
  • Lisinopril (Prinivil, Zestril)
  • Moexipril (Univasc)
  • Perindopril (Aceon)
  • Quinapril (Accupril)
  • Ramipril (Altace)
  • Trandolapril (Mavik

Angiotensin Receptor Blockers (ARBs)

  • Atacand (Candesartan)
  • Teveten (Eprosartan)
  • Avapro (Irbesartan)
  • Cozaar (Losartan)
  • Benicar (Olmesartan)
  • Micardis (Telmisartan)
  • Diovan (Valsartan)

Antibiotics

Okay, this one could potentially be a very long list so I'll just list the more common ones.

  • Amoxicillin (Amoxil)
  • Ampicillin (Principen)
  • Azithromycin (Zithromax)
  • Cefazolin (Ancef)
  • Cefprozil (Cefzil)
  • Ceftriaxone (Rocephin)
  • Cephalexin (Keflex)
  • Ciprofloxacin (Cipro)
  • Clarithromycin (Biaxin)
  • Clindamycin (Cleocin)
  • Doxycycline (Doryx, Vibramycin)
  • Ertapenem (Invanz)
  • Erythromycin (E-Mycin)
  • Gentamicin
  • Meropenem (Merrem)
  • Metronidazole (Flagyl)
  • Minocycline (Minocin)
  • Nalidixic acid (Neggram)
  • Penicillin (Pen Vee K)
  • Sulfamethoxazole-Trimethoprim (Bactrim, Spetra)
  • Tetracycline (Sumycin)
  • Tobramycin

COX-2 Inhibitors

  • Celecoxib (Celebrex)
  • Valdecoxib (Bextra)

Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)

  • Diclofenac potassium (Cataflam)
  • Diclofenac sodium (Voltaren, Voltaren XR)
  • Diflunisal (Dolobid)
  • Etodolac (Lodine, Lodine XL)
  • Fenoprofen (Nalfon)
  • Flurbiprofen (Ansaid)
  • Ibuprofen (Advil, Motrin, Motrin IB, Nuprin)
  • Indomethacin (Indocin)
  • Ketoprofen (Actron, Orudis, Orudis KT, Oruvail)
  • Meclofenamate (Meclomen)
  • Mefenamic acid (Ponstel)
  • Nabumetone (Relafen)
  • Naproxen (Aleve, Anaprox, Naprelan, Naprosyn, Naprosyn-E)
  • Oxaprozin (Daypro)
  • Piroxicam (Feldene)
  • Sulindac (Clinoril)
  • Tolmetin (Tolectin)

Proton Pump Inhibitors (PPIs)

  • Dexlansoprazole (Kapidex)
  • Esomeprazole (Nexium)
  • Lansoprazole (Prevacid)
  • Omeprazole (Prilosec, Prilosec OTC)
  • Pantoprazole (Protonix)
  • Rabeprazole (Aciphex)

Selective Serotonin Reuptake Inhibitors (SSRIs)

Statins

Sulfa Drugs

  • Acetazolamide (Diamox)
  • Bumetanide (Bumex)
  • Celecoxib (Celebrex)
  • Chlorpropamide (Diabinese)
  • Chlorthalidone (Thalitone)
  • Darunavir (Prezista)
  • Dorzolamide (Trusopt)
  • Furosemide (Lasix)
  • Glipizide (Glucotrol, Glucotrol XL)
  • Glyburide (Diabeta, Glynase, Micronase)
  • Hydrochlorothiazide (Esidrix, Microzide)
  • Indapamide (Lozol)
  • Metolazone (Mykrox, Zaroxolyn)
  • Probenecid
  • Sulfacetamide
  • Sulfadiazine
  • Sulfadoxine
  • Sulfamethoxazole
  • Sulfanilamide
  • Sulfasalazine (Azulfidine)
  • Sulfisoxazole (Gantrisin)
  • Sumatriptan (Imitrex)
  • Tolazamide (Tolinase)
  • Tolbutamide
  • Zonisamide (Zonegran)

Vaccines

  • Anthrax
  • Chickenpox (Varicella)
  • DTaP (Diphtheria, Tetanus, and acellular Pertussis)
  • Hepatitis A
  • Hepatitis B
  • Hib (Haemophilus influenzae type b)
  • Influenza
  • HPV (Human Papillomavirus)
  • Japanese Encephalitis
  • Lyme Disease
  • MMR (Measles, Mumps, and Rubella)
  • Meningococcal
  • PCV-7 (Pneumococcal conjugate)
  • PPV-23 (Pneumococcal polysaccharide)
  • Polio
  • Rabies
  • Rotavirus
  • Shingles (Herpes zoster)
  • Smallpox
  • Td and TdaP
  • Typhoid fever
  • Yellow fever

Other Medications


The most suitable gift for the
man who has everything
-a shot of antibiotics.




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June 27, 2009


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